Blog | Tuesday, October 28, 2008

Drugs to keep an eye on


As we reported in ACP Internist Weekly today, a record number of deaths and serious injuries from prescription drugs were reported to the FDA in the first quarter of 2008, according to the non-profit Institute for Safe Medication Practices (ISMP).

I thought it might be interesting to show the ISMP's chart of the top ten drugs in terms of adverse events and deaths. So here we go:

Drugs, ranked by reported # of serious adverse events:

VARENICLINE: 1001 events
HEPARIN: 779
FENTANYL: 631
INTERFERON BETA: 582
INFLIXIMAB: 463
ETANERCEPT: 401
CLOPIDOGREL: 297
PREGABALIN: 280
ACETAMINOPHEN: 273
OXYCODONE: 272

Drugs, ranked by reported # of deaths:

OXYCODONE: 185 deaths
ALPRAZOLAM: 163
ACETAMINOPHEN: 160
ACETAMINOPHEN; BUTALBITAL; CAFFEINE (combo drug): 156
FENTANYL: 131
MORPHINE: 115
IBUPROFEN: 114
METHADONE: 111
ACETAMINOPHEN; HYDROCODONE (combo): 111
HEPARIN: 102