Blog | Wednesday, May 11, 2011

Electronic pancreas may keep glucose in safe range overnight


A team led by researchers from University of Cambridge showed that closed loop insulin delivery was effective in controlling overnight blood glucose levels in patients with type 1 diabetes. The system took readings every fifteen minutes and automatically titrated a proper amount of insulin.

University of Cambridge researcher Dr. Roman Hovorka led two studies to evaluate the performance of the artificial pancreas in 10 men and 14 women, aged 18 to 65, who had used an insulin pump for at least three months.

The first study monitored 12 participants overnight after consuming a medium-sized meal (60 g carbohydrate) at 7 p.m. In the second study, the other 12 participants were monitored overnight after consuming a larger meal (100 g carbohydrate) accompanied by alcohol at 8.30 p.m.

The studies showed a 22% improvement in the time participants kept their blood glucose levels in a safe range, halving the time they spent with low blood glucose levels and reducing the risk of both short term and long term complications.

Link at Cambridge: Artificial pancreas promise for common diabetes complication ...

Abstract in BMJ: Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies

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