Blog | Wednesday, April 25, 2012

QD: News Every Day--Statins don't lower melanoma rates

There was no significant association between statin use and melanoma risk among postmenopausal women, according to a study of data from the Women's Health Initiative.

Lab studies and one trial offered some hope that the ubiquitous cholesterol drugs might have an protective effect on skin cells as well, but as one dermatologist commented to Reuters, "[W]e're putting the nail into the coffin of that theory."

Researchers looked at nearly 120,000 postmenopausal white women, in which nearly 1,100 cases of malignant melanoma were identified over an average of more than 11 years.

Cancer was confirmed from medical records, while statin use was self-reported. Statins were used by 8,824 women (7.4%) at baseline. Melanoma occurred equally in statin users and nonusers (multivariable adjusted hazard ratio, 1.14; 95% confidence interval, 0.91 to 1.43). Statin type, potency, category or duration didn't matter, researchers reported in the journal Cancer.