Sublingual drops for asthma work just as well as injections, a meta-analysis found.
Researchers reviewed outcomes for injections of 13 trials with 920 children and 18 studies of 1,583 children who received drops. All trials were randomized controlled trials of children with allergic asthma or rhinoconjunctivitis. Only three of the 34 studies directly compared shots and drops.
href="http://pediatrics.aappublications.org/content/early/2013/04/30/peds.2013-0343.abstract"Results appeared in the May 6 issue of Pediatrics.
There was moderate strength of evidence that injections improved asthma and rhinitis symptoms and low strength of evidence that injections improved conjunctivitis symptoms and asthma medication scores. Strength of evidence is high that drops improved asthma symptoms and moderate that they improved rhinitis and conjunctivitis symptoms and decreases medication use.
There was little evidence to support using injections over drops, the authors noted. The three studies that directly compared injections versus drops for dust mite-induced asthma and rhinitis showed no strong evidence that shots worked better than drops.